Два чувства нас спасают в жизни — любовь и юмор…
Если у вас есть одно из двух, вы — счастливый человек!
Если у вас есть оба… — вы непобедимы! :)
Humor is Life, Apathy is Death.
Все остальное Юмор! Юмор исцеляет все :)
Как хорошо быть свободной от всего...
От страхов, стереотипов, условностей, ценностей, смешных законов...
Все это пыль для меня, чушь... Вызывает лишь смех...
ALL IS HUMOR.
At the University of Wisconsin, scientists have stumbled upon the ''completely accidental discovery of skin cells that do not die.''
Dr. Lynn Allen-Hoffmann, professor of pathology and director of the laboratory in which the cells reside, has demonstrated that these cells are in fact immortal.
Immortal human skin
According to an Earthfiles article by Linda Moulton Howe, ''It all started in early 1996 at the end of a research project in which Dr. Allen-Hoffmann and her lab assistants had been growing human skin cells in culture dishes over several weeks. In one set of dishes, she was testing a chemical additive on tissue. Another series of dishes had nothing added so she would have a normal control for comparison. Strangely, and still mystifying, one of the control dishes was different from all others.''
Briefly, long after the other cells had died a normal death, the cells in this control dish were still growing!
''When the miraculous cells were still alive and thriving after an entire year,'' Howe wrote, ''instead of dying after a few weeks like normal skin, the University of Wisconsin Alumni Research Foundation patented the cells now known as 'NIKS.' That acronym stands for Near-Diploid Immortal Keratinocytes. The acronym also represents the lab's sense of humor. NIKS is SKIN spelled backwards.''
Howe interviewed Dr. Allen-Hoffman, who said, ''[I]t was in one of those control cell plates that my technician, Sandy Schlosser, noticed — and this was on the day we were literally going to fix — and by fix, I mean formaldehyde-preserve, these cells, which would totally have terminated the experiment. Anything living in there would have been killed. We noticed there was a small colony of cells that had a phenotype that is called basal. They looked as if they were actively growing. They were small and very uniform in size and she came into my office and said, 'Lynn, come and take a look.'
''And I went in and looked at this and she asked me what it was and I said, 'You know, that looks like an actively growing colony and this is very unusual. I don't know for sure what it is.' Why would that colony be living when clearly all the other cells in the dish were senescent?
''And what was astounding to us was that this cell line that has this immortal growth characteristic is amazingly similar to the original parental cells. We were expecting to see some biochemical differences, some structural differences in the cells in culture, and we thus far have not observed that. We have looked to see if they exhibit any characteristics that would lead us to believe they are cancerous or pre-cancerous and the answer to that is no.''
Howe asked Dr. Allen-Hoffmann whether it would be possible to produce large quantities of this immortal human skin, noting that it would be especially useful for working with burn victims.
''Yes,'' she answered, ''and that is a really important question. We're doing animal grafting studies now with the NIKS cell graft to determine if we can indeed do that and if we can successfully get the cells grafted on to animal models. We have a lot of really exciting work to be done yet with regard to demonstrating that this will be a therapeutic value to the medical community. And we're excited about positioning ourselves so we can go forward with those types of experiments.''
What the doctors don't yet know is why these cells are immortal. However, they have shown that genome-sequencing is involved. The difference involves just a very small change in the cell's genetic material.
And if skin cells can be made immortal, of course we have to ask whether a small change to human DNA might not confer immortality upon the whole body.
You can read more about these immortal cells at Linda Howe's website, earthfiles.com.
Если у вас есть одно из двух, вы — счастливый человек!
Если у вас есть оба… — вы непобедимы! :)
Humor is Life, Apathy is Death.
Все остальное Юмор! Юмор исцеляет все :)
Как хорошо быть свободной от всего...
От страхов, стереотипов, условностей, ценностей, смешных законов...
Все это пыль для меня, чушь... Вызывает лишь смех...
ALL IS HUMOR.
At the University of Wisconsin, scientists have stumbled upon the ''completely accidental discovery of skin cells that do not die.''
Dr. Lynn Allen-Hoffmann, professor of pathology and director of the laboratory in which the cells reside, has demonstrated that these cells are in fact immortal.
Immortal human skin
According to an Earthfiles article by Linda Moulton Howe, ''It all started in early 1996 at the end of a research project in which Dr. Allen-Hoffmann and her lab assistants had been growing human skin cells in culture dishes over several weeks. In one set of dishes, she was testing a chemical additive on tissue. Another series of dishes had nothing added so she would have a normal control for comparison. Strangely, and still mystifying, one of the control dishes was different from all others.''
Briefly, long after the other cells had died a normal death, the cells in this control dish were still growing!
''When the miraculous cells were still alive and thriving after an entire year,'' Howe wrote, ''instead of dying after a few weeks like normal skin, the University of Wisconsin Alumni Research Foundation patented the cells now known as 'NIKS.' That acronym stands for Near-Diploid Immortal Keratinocytes. The acronym also represents the lab's sense of humor. NIKS is SKIN spelled backwards.''
Howe interviewed Dr. Allen-Hoffman, who said, ''[I]t was in one of those control cell plates that my technician, Sandy Schlosser, noticed — and this was on the day we were literally going to fix — and by fix, I mean formaldehyde-preserve, these cells, which would totally have terminated the experiment. Anything living in there would have been killed. We noticed there was a small colony of cells that had a phenotype that is called basal. They looked as if they were actively growing. They were small and very uniform in size and she came into my office and said, 'Lynn, come and take a look.'
''And I went in and looked at this and she asked me what it was and I said, 'You know, that looks like an actively growing colony and this is very unusual. I don't know for sure what it is.' Why would that colony be living when clearly all the other cells in the dish were senescent?
''And what was astounding to us was that this cell line that has this immortal growth characteristic is amazingly similar to the original parental cells. We were expecting to see some biochemical differences, some structural differences in the cells in culture, and we thus far have not observed that. We have looked to see if they exhibit any characteristics that would lead us to believe they are cancerous or pre-cancerous and the answer to that is no.''
Howe asked Dr. Allen-Hoffmann whether it would be possible to produce large quantities of this immortal human skin, noting that it would be especially useful for working with burn victims.
''Yes,'' she answered, ''and that is a really important question. We're doing animal grafting studies now with the NIKS cell graft to determine if we can indeed do that and if we can successfully get the cells grafted on to animal models. We have a lot of really exciting work to be done yet with regard to demonstrating that this will be a therapeutic value to the medical community. And we're excited about positioning ourselves so we can go forward with those types of experiments.''
What the doctors don't yet know is why these cells are immortal. However, they have shown that genome-sequencing is involved. The difference involves just a very small change in the cell's genetic material.
And if skin cells can be made immortal, of course we have to ask whether a small change to human DNA might not confer immortality upon the whole body.
You can read more about these immortal cells at Linda Howe's website, earthfiles.com.
